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Identification of new genovariants of canine distemper virus in dogs from the State of el análisis del gen de la nucleocápside en perros del Estado de México.

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Canine distemper is caused by a single-stranded RNA virus of the family Paramyxoviridae the same family of the viruses that causes measlesmumpsand bronchiolitis in humans. The mortality rate of the virus largely depends on the immune status of the infected dogs. These are some of the reasons why the N gene is a candidate for studies; also the sequences of this gene allow the differentiation among the strains of CDV Simon-Martinez et al The results show the formation of two main groups, one that includes only the isolates of the State of Mexico, and another formed by two sub-groups.

Canine distemper virus tends to orient its infection towards the lymphoidepithelialand nervous tissues. Despite extensive vaccination in many regions, it remains a major disease of dogs.

Distemper Canino

Globally, Canine Distemper Disease is one of the most important viral diseases disteper dogs due to its high mortality and morbidity. Infected animals should be quarantined from other dogs for several months owing to the length of time the animal may shed the virus. The virus then enters the blood stream and infects the respiratorygastrointestinalurogenitalepithelial, and central nervous systemsand optic nerves.

A thickening of the footpads sometimes develops, and vesicular pustular lesions dstemper the abdomen usually develop.

Multiple alignments of 74 amino acids of vaccine strain Onderstepoort AF and 11 pathogenic strains reported in GenBank. It can also be spread by food and water contaminated with these fluids.

J Vet Sci 2, Examples include administering fluids, electrolyte solutions, analgesics, anticonvulsants, broad-spectrum antibiotics, antipyretics, parenteral nutrition, and nursing care. Outbreaks of canine distemper continue to occur throughout the United States distempwr elsewhere, and are caused by many factors, including proximity to wild animals and lack of vaccinated animals.


It also may have played a considerable role in the extinction of the thylacine Tasmanian tiger and recurrently causes mortality among African wild dogs. Canine distemper virus affects nearly all body systems. However, due to inconsistencies on the extremes of the obtained sequences, these were edited considering only bp for the phylogenetic analysis corresponding to nucleotides to of the N gen. The virus then enters the bloodstream on the second or third day.

The friendly and inquisitive LaPerm has an easy-care coat that comes in a variety of colors and patterns. Canine distemper sometimes termed hardpad disease is a viral disease that affects a wide variety of animal families, including domestic and wild species of dogs, coyotes, foxes, pandas, wolves, ferrets, skunks, raccoons, and large cats, as well as pinnipeds, some primates, and a variety of other species.

Journal of Zoo and Wildlife Medicine.

Distemper Canino

In older dogs that develop distemper encephalomyelitis, diagnosis may be more difficult, since many of these dogs have an adequate vaccination history. The results obtained showed that different isolates genetically related are circulating in this region and they are exclusive of Mexico; a similar situation has been previously described for other isolates in other countries Yoshida et alCastilho et al Consensus sequence of another 15 strains reported in GenBank and all genovariants reported in this study.

Archived copy as title All articles lacking reliable references Articles lacking reliable references from December Wikipedia articles needing page number citations from December All pages needing factual verification Wikipedia articles needing factual verification from December Articles with ‘species’ microformats All articles with unsourced statements Articles with unsourced statements from December Commons category link is on Wikidata Wikipedia articles with BNF identifiers Wikipedia articles with LCCN identifiers Wikipedia articles with SUDOC identifiers.

Archived from the original on 12 March Puppies experience the highest mortality rate, where complications such as pneumonia and encephalitis are more common. The data analysis was performed using molecular distmeper.

Canine distemper – Wikipedia

Ecosystems and human well-being. As with measles, the treatment is symptomatic and supportive. Vet Microbiol 44, The disease is highly contagious via inhalation. In the Neighbor-joining tree, the creations of two principal clades or groups were observed.

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Without the full series of shots, the vaccination does not provide protection against the virus. Retrieved from ” https: The results showed that N gene sequences belong to seven Canine Distemper Virus genovariants distekper had never been distemler before in the State of Mexico. CDV has an envelope composed of a membrane protein termed M and two glycoproteins, the hemagglutinin termed H and the fusion protein termed F Mochizuki et al ; the genomic RNA is tightly bound to the nucleocapsid protein, termed N; the major structural protein.

Jorge Guerrero November 6, Identification of a genetic variant of canine distemper virus from clinical cases in two vaccinated dogs in Mexico.

Secuencia consenso de otras 15 cepas reportadas y todas las genovariantes reportadas en este diistemper.

Mol Biol Evol 24, Perrox from the original on June 25, Epidemiological studies of the disease in this country have not been made, probably due to the lack of information about the molecular characteristics of the CDV isolates in the different geographical areas of this country. Animals in the family Felidaeincluding many species of large cat as well as domestic cats, were long believed to be resistant to canine distemper, until some researchers reported the prevalence of CDV infection in large felids.

This page was last edited on 26 Decemberat Characterization of monoclonal antibodies directed against the canine distemper virus perrros protein.

Distemper is caused by a single-stranded RNA virus of the family Paramyxoviridaewhich is a close relative of the viruses that cause measles in humans and rinderpest in animals.